Explore a selection of works produced by faculty in the Department of Biomedical Engineering at Michigan Technological University.

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Submissions from 2018

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Effect of incorporating clustered silica nanoparticles on the performance and biocompatibility of catechol-containing PEG-based bioadhesive, Rattapol Pinnaratip, Hao Meng, Rupak Rajachar, and Bruce P. Lee

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Bioengineering scaffolds for regenerative engineering, Zichen Qian, Daniel Radke, Wenkai Jia, Mitchell D. Tahtinen, Guifang Wang, and Feng Zhao

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Bioactive polydimethylsiloxane surface for optimal human mesenchymal stem cell sheet culture, Zichen Qian, David Ross, Wenkai Jia, Qi Xing, and Feng Zhao

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Tissue Engineering at the Blood-Contacting Surface: A Review of Challenges and Strategies in Vascular Graft Development., Daniel Radke, Wenkai Jia, Dhavan Sharma, Kemin Fena, Guifang Wang, Jeremy Goldman, and Feng Zhao

Mesenchymal stem cells for pre-vascularization of engineered tissues, Dhavan Sharma, Juan Felipe Chica, and Feng Zhao

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Application of composite hydrogels to control physical properties in tissue engineering and regenerative medicine, Cassidy Sheffield, Kaylee Meyers, Emil Johnson, and Rupak Rajachar

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Assessing the reliability of pulsatility in four-dimensional digital subtraction angiography time concentration curves, Jimmy Xu, Gabe Shaughnessy, Sebastian Schafer, Jingfeng Jiang, Charles Mistretta, and Charles M. Strother

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Prevascularization of natural nanofibrous extracellular matrix for engineering completely biological three-dimensional prevascularized tissues for diverse applications., Lijun Zhang, Zichen Qian, Mitchell D. Tahtinen, Shaohai Qi, and Feng Zhao

Works from 2017

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Effect of PLLA coating on corrosion and biocompatibility of zinc in vascular environment, Avishan Arab Shomali, Roger J. Guillory II, Daniel Seguin, Jeremy Goldman, and Jaroslaw W. Drelich

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Evaluation of wrought Zn–Al alloys (1, 3, and 5 wt % Al) through mechanical and in vivo testing for stent applications, Patrick Bowen, Jan-Marten Seitz, Roger J. Guillory II, Jacob P. Braykovich, Shan Zhao, Jeremy Goldman, and Jaroslaw W Drelich

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Pre-vascularization enhances therapeutic effects of human mesenchymal stem cell sheets in full thickness skin wound repair, Lei Chen, Qi Xing, Qiyi Zhai, Mitchell Tahtinen, Fei Zhou, Lili Chen, Yingbin Xu, Shaohai Qi, and Feng Zhao

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Long-term surveillance of zinc implant in murine artery: Surprisingly steady biocorrosion rate, Adam J. Drelich, Shan Zhao, Roger J. Guillory II, Jaroslaw Drelich, and Jeremy Goldman

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Catechol redox reaction: reactive oxygen species generation, regulation, and biomedical applications, Pegah Kord Forooshani, Hao Meng, and Bruce P. Lee

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Improving the Performance of Implantable Sensors with Nitric Oxide Release, Megan C. Frost

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Novel high-strength, low-alloys Zn-Mg (< 0.1 wt% Mg) and their arterial biodegradation, Hualan Jin, Shan Zhao, Roger J. Guillory II, Patrick Bowen, Zhiyong Yin, Adam Griebel, Jeremy Schaffer, Elisha J. Early, Jeremy Goldman, and Jaroslaw W. Drelich

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The Prospects of Zinc as a Structural Material for Biodegradable Implants—A Review Paper, Galit Katarivas Levy, Jeremy Goldman, and Eli Aghion

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Evaluation of biodegradable Zn-1%Mg and Zn-1%Mg-0.5%Ca alloys for biomedical applications, Galit Katarivas Levy, Avi Leon, Alon Kafri, Yvonne Ventura, Jaroslaw Drelich, Jeremy Goldman, Razi Vago, and Eli Aghion

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A moldable nanocomposite hydrogel composed of a mussel‐inspired polymer and a nanosilicate as a fit‐to‐shape tissue sealant, Yuan Liu, Hao Meng, Zichen Qian, Ni Fan, Wonyoung Choi, Feng Zhao, and Bruce Lee

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Effect of ionic functional groups on the oxidation state and interfacial binding property of Catechol-based adhesive, Ameya Ravindra Narkar; Jonathan D, Kelley; Rattapol Pinnaratip; and Bruce P. Lee

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Effects of short term hypoxia-preconditioning on glial phenotype induction of human mesenchymal stem cells, Zichen Qian, Qi Xing, Corey Fase, Kyle Jansen, and Feng Zhao

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Aligned nanofibrous cell‐derived extracellular matrix for anisotropic vascular graft construction, Qi Xing, Zichen Qian, Mitchell D. Tahtinen, Ai Hui Yap, Keegan Yates, and Feng Zhao

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Structural characteristics and in vitro biodegradatation of a novel ZnLi alloy prepared by induction melting and hot rolling, Shan Zhao, Cameron McNamara, Patrick Bowen, Nicholas Verhun, Jacob P. Braykovich, Jeremy Goldman, and Jaroslaw W. Drelich

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Zn-Li alloy after extrusion and drawing: Structural, mechanical characterization, and biodegradation in abdominal aorta of rat, Shan Zhao, Jan-M Seitz, Ranier Eifler, Hans J. Maier, Roger J. Guillory II, Elisha J. Earley, Adam J. Drelich, Jeremy Goldman, and Jaroslaw Drelich

Works from 2016

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Biodegradable metals for cardiovascular stents: from clinical concerns to recent Zn‐alloys, Patrick Bowen, Emily Shearier, S. Zhao, Roger J. Guillory II, Feng Zhao, Jeremy Goldman, and Jaroslaw Drelich

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Importance of oxide film in endovascular biodegradable zinc stents, Adam J. Drelich, Patrick Bowen, Leslie LaLonde, Jeremy Goldman, and Jaroslaw W Drelich

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Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein, Pegah Kord Forooshani and Bruce P. Lee

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Corrosion characteristics dictate the long-term inflammatory profile of degradable zinc arterial implants, Roger J. Guillory II, Patrick Bowen, Sean Hopkins, Emily Shearier, Elisha J. Earley, Amani Gillette, and et al.

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Mussel adhesive-inspired polymers, Bruce P. Lee

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Effect of metal ion type on the movement of hydrogel actuator based on catechol-metal ion coordination chemistry, Bruce P. Lee, Ameya Narkar, and Randall Wilharm

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Biomimetic adhesives and coatings based on Mussel adhesive Proteins, Yuan Lin, Hao Meng, P. B. Messersmith, Bruce P. Lee, and Jeffrey L. Dalsin

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Iterative l1-min algorithm for fixed pattern noise removal in fiber-bundle-based endoscopic imaging, Xuan Liu, Lijun Zhang, Mitchell Kirby, Richard Becker, Shaohai Qi, and Feng Zhao

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Recovery property of double-network hydrogel containing mussel-inspired adhesive moiety and nano-silicate, Yuan Liu and Bruce P. Lee

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Gelatin microgel incorporated poly(ethylene glycol)-based bioadhesive with enhanced adhesive property and bioactivity, Yuting Li, Hao Meng, Yuan Liu, Ameya Narkar, and Bruce P. Lee

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Model polymer system for investigating the generation of hydrogen peroxide and its biological responses during the crosslinking of mussel adhesive moiety, Hao Meng, Yuan Liu, and Bruce P. Lee

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pH responsive and oxidation resistant wet adhesive based on reversible catechol–boronate complexation, Ameya R. Narkar, Brett Barker, Matthew Clisch, Jingfeng Jiang, and Bruce P. Lee

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In vitro cytotoxicity, adhesion, and proliferation of human vascular cells exposed to zinc, Emily Shearier, Patrick Bowen, Weilue He, Adam J. Drelich, Jaroslaw Drelich, Jeremy Goldman, and Feng Zhao

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Bioactive vapor deposited calcium-phosphate silica sol–gel particles for directing osteoblast behavior, Katherine L. Snyder, Hallie R. Holmes, Connor McCarthy, and Rupak M. Rajachar

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Altered Cytoskeleton as a Mitochondrial Decay Signature in the Retinal Pigment Epithelium, Srinivas R. Sripathi, Weilue He, O’Donnell D. Sylvester, Musa Neksumi, Ji Yeon Um, Thagriki Dluya, Paul S. Bernstein, and Wan Jin Jahng

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VesselMap: A web interface to explore multivariate vascular data, Jun Tao, Xiaoke Huang, Feng Qiu, Chaoli Wang, Jingfeng Jiang, Ching Kuan Shene, Ye Zhao, and Daphne Yu

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In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel, Shuo Wang, Oju Jeon, Peter G. Shankles, Yuan Liu, Eben Alsberg, Scott T. Retterer, Bruce P. Lee, and Chang Kyoung Choi

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Natural extracellular matrix for cellular and tissue biomanufacturing, Qi Xing, Zichen Qian, Wenkai Jai, Avik Ghosh, Mitchell D. Tahtinen, and Feng Zhao

Works from 2015

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Increased corrosion resistance of the AZ80 magnesium alloy by rapid solidification, E. Aghion, L. Jan, L. Meshi, and J. Goldman

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Corrosion behavior of nano/sub-micron F401 titanium alloy, Eli Aghion, Inbar Guinguis, and Jeremy Goldman

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Wireless magnetoelastic sensors for tracking degradation profiles of nitrodopamine-modified poly(ethylene glycol), Jonathan Anderson, Meng-Hsien Lin, Caitlyn Privette, Marissa Flowers, Meridith Murley, Bruce P. Lee, and Keat Ghee Ong

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Metallic zinc exhibits optimal biocompatibility for bioabsorbable endovascular stents, Patrick Bowen, Roger J. Guillory II, Emily Shearier, Jan-Marten Seitz, Jaroslaw W. Drelich, Martin Bocks, Feng Zhao, and Jeremy Goldman

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Nitro-group functionalization of dopamine and its contribution to the viscoelastic properties of catechol-containing nanocomposite hydrogels, Xiaochu Ding, Giri K. Vegesna, Hao Meng, Audra Winter, and Bruce P. Lee

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The application of biomedical engineering techniques to the diagnosis and management of tropical diseases: A review, Fatimah Ibrahim, Tzer Hwai Gilbert Thio, Tarig Faisal, and Michael Neuman

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Modulating the movement of hydrogel actuator based on catechol-iron ion coordination chemistry, Bruce P. Lee, Meng-Hsien Lin, Ameya Narkar, Shari Konst, and Randall Wilharm

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Monitoring the long-term degradation behavior of biomimetic bioadhesive using wireless magnetoelastic sensor, Meng-Hsien Lin, Jonathan Anderson, Rattapol Pinnaratip, Hao Meng, Shari Konst, Andrew J. DeRouin, Rupak Rajachar, Keat Ghee Ong, and Bruce P. Lee

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Motion analysis and removal in intensity variation based OCT microangiography, Xuan Liu, Mitchell Kirby, and Feng Zhao

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Dark-field illuminated fiber bundle endoscopy with iterative l1-min image reconstruction for honeycomb pattern removal, Xuan Liu, Lijun Zhang, Mitchell Kirby, Divyaansh Raj, Shaohai Qi, and Feng Zhao

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Biomimetic approach to designing adhesive hydrogels: from chemistry to application, Yuting Li and Bruce P. Lee

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Fibrin gel as an injectable biodegradable scaffold and cell carrier for tissue engineering, Yuting Li, Hao Meng, Yuan Liu, and Bruce P. Lee

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Electrospinning 3D scaffolds for use in neural tissue engineering, Rachel Martin, M. E. Mullins, F. Zhao, and Zichen Qian

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Fabrication and short-term in vivo performance of a natural elastic lamina–polymeric hybrid vascular graft, Connor W. McCarthy, Danielle C. Ahrens, David Joda, Tyler E. Curtis, Patrick Bowen, Roger J. Guillory II, Shu Q. Liu, Feng Zhao, Megan C. Frost, and Jeremy Goldman

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Adhesives and coatings inspired by mussel adhesive proteins, Hao Meng, Morgan M. Cencer, and Bruce P. Lee

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Adhesives and Coatings Inspired by Mussel Adhesive Proteins, Hao Meng, Yuan Liu, Morgan M. Cencer, and Bruce P. Lee

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Hydrogen peroxide generation and biocompatibility of hydrogel-bound mussel adhesive moiety, Hao Meng, Yuting Li, Madeline Faust, Shari Konst, and Bruce P. Lee

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Recent advances in biodegradable metals for medical sutures: A critical review, Jan-Marten Seitz, Martin Durisin, Jeremy Goldman, and Jaroslaw W Drelich

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Surface defection reduces cytotoxicity of Zn(2- methylimidazole)2 (ZIF-8) without compromising its drug delivery capacity, Emily Shearier, Peifu Cheng, Zhuan Zhu, Jiming Bao, Yun Hang Hu, and Feng Zhao

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Surfactant-assisted Hydrothermal Synthesis of Fluoridated Hydroxyapatite Nanorods, Mohammad Mahdi Taheri, Mohammed Rafiq Abdul Kadir, Tolou Shokuhfar, Azhang Hamlekhan, Mahtab Assadian, Mostafa Rezazadeh Shirdar, and Abolfazl Mirjalili

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Biocompatibility of MgF2 -coated MgNd2 specimens in contact with mucosa of the nasal sinus-A long term study, Constantin M. Weber, Rainer Eifler, Jan Marten Seitz, Hans J. Maier, Janin Reifenrath, Thomas Lenarz, and Martin Durisin

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Is there value in chemical modification of fish scale surfaces?, Xu Xiang, Fei Long, Ameya Narkar, Ronald E. Kinnunen, Reza Shahbazian-Yassar, Bruce P. Lee, and Patricia A. Heiden

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Osteogenic differentiation evaluation of an engineered extracellular matrix based tissue sheet for potential periosteum replacement, Qi Xing, Zichen Qian, Baratwaaj Kannan, Mitchell D. Tahtinen, and Feng Zhao

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Nitric oxide regulates cell behavior on an interactive cell-derived extracellular matrix scaffold., Qi Xing, Lijun Zhang, Travis Redman, Shaohai Qi, and Feng Zhao

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Hypoxia Created Human Mesenchymal Stem Cell Sheet for Prevascularized 3D Tissue Construction, Lijun Zhang, Qi Xing, Zichen Qian, Mitchell D. Tahtinen, Zhaoqiang Zhang, Emily Shearier, Shaohai Qi, and Feng Zhao

Works from 2014

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Characterizing the dielectric properties of human mesenchymal stem cells and the effects of charged elastin-like polypeptide copolymer treatment, T. N. G. Adams, P. A. Turner, A. V. Janorkar, F. Zhao, and A. R. Minerick

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Rates of in vivo (arterial) and in vitro biocorrosion for pure magnesium, Patrick Bowen, Adam J. Drelich, Jaroslaw Drelich, and Jeremy Goldman

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Magnesium in the murine artery: Probing the products of corrosion, Patrick Bowen, Jaroslaw Drelich, and Jeremy Goldman

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Effect of pH on the rate of curing and bioadhesive properties of dopamine functionalized poly(ethylene glycol) hydrogels, Morgan Cencer, Yuan Liu, Audra Winter, Meridith Murley, Hao Meng, and Bruce P. Lee

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Effect of nitro-functionalization on the cross-linking and bioadhesion of biomimetic adhesive moiety, Morgan Cencer, Meridith Murley, Yuan Lin, and Bruce P. Lee

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Novel hydrogel actuator inspired by reversible mussel adhesive protein chemistry, Bruce P. Lee and Shari Konst

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Novel hydrogel actuator based on biomimetic chemistry, Bruce P. Lee, Yuan Liu, and Shari Konst

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Motion analysis and removal in intensity variation based OCT angiography, Xuan Liu, Mitchell Kirby, and Feng Zhao

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Injectable dopamine-modified poly(ethylene glycol) nanocomposite hydrogel with enhanced adhesive property and bioactivity, Yuan Liu, Hao Meng, Shari Konst, Ryan Sarmiento, Rupak Rajachar, and Bruce P. Lee

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Current approaches to designing nanomaterials inspired by mussel adhesive proteins, Hao Meng, Joseph Gazella, and Bruce P. Lee

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Application of sub-micrometer vibrations to mitigate bacterial adhesion, Will R. Paces, Hal Holmes, Eli Vlaisavljevich, Katherine L. Snyder, Ee Lim Tan, Rupak Rajachar, and Keat Ghee Ong

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Highly aligned nanofibrous scaffold derived from decellularized human fibroblasts, Qi Xing, Caleb Vogt, Kam W. Leong, and Feng Zhao

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Decellularization of fibroblast cell sheets for natural extracellular matrix scaffold preparation, Qi Xing, Keegan Yates, Mitchell D. Tahtinen, Emily Shearier, Zichen Qian, and Feng Zhao

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Response of endothelial cells to decellularized extracellular matrix deposited by bone marrow mesenchymal stem cells., Yue Xu, Mengdie Yan, Yihong Gong, Lei Chen, Feng Zhao, and Zhaoqiang Zhang

Works from 2013

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A new in vitro–in vivo correlation for bioabsorbable magnesium stents from mechanical behavior, Patrick Bowen, Jaroslaw W. Drelich, and Jeremy Goldman

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Zinc exhibits physiological corrosion behavior for bioabsorbable stents, Patrick Bowen, Jaroslaw W. Drelich, and Jeremy Goldman

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Inducible nitric oxide releasing poly-(ethylene glycol)-fibrinogen adhesive hydrogels for tissue regeneration, Margaret A. Brunette, Hal Holmes, Michael Lancina, Weilue He, Bruce P. Lee, Megan C. Frost, and Rupak Rajachar

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Marine adhesive containing nanocomposite hydrogel with enhanced materials and bioadhesive properties, Yuan Liu, Hao Zhan, Sarah Skelton, and Bruce P. Lee

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Automated Methods to Determine Electrospun Fiber Alignment and Diameter Using the Radon Transform, Nicholas J. Schaub, Sean J. Kirkpatrick, and Ryan J. Gilbert

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Biomimetic adhesive containing nanocomposite hydrogel with enhanced materials properties, Sarah Skelton, Michael Bostwick, Kyle O'Connor, Shari Konst, Samuel Casey, and Bruce P. Lee

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Development of vapor deposited silica sol-gel particles for use as a bioactive materials system, Katherine L. Snyder, Hallie R. Holmes, Michael J. Vanwagner, Natalie J. Hartman, and Rupak M. Rajachar

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S-nitroso-N-acetylpenicillamine (SNAP) derivatization of peptide primary amines to create inducible nitric oxide donor biomaterials, Michael VanWagner, Jessica Rhadigan, Michael Lancina, Allison Lebovsky, Genevieve Romanowicz, Hal Holmes, Margaret A. Brunette, Katherine L. Snyder, Michael Bostwick, Bruce P. Lee, Megan C. Frost, and Rupak Rajachar

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Magnetoelastic vibrational biomaterials for real-time monitoring and modulation of the host response, E. Vlaisavljevich, H. R. Holmes, E. L. Tan, Z. Qian, S. Trierweiler, K. Ghee Ong, and R. M. Rajachar

Works from 2012

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New approaches in evaluating metallic candidates for bioabsorbable stents, Patrick Bowen, Jaroslaw W. Drelich, Robert E. Buxmaum, Rupak Rajachar, and Jeremy Goldman

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Tensile testing as a novel method for quantitatively evaluating bioabsorbable material degradation, Patrick Bowen, Jesse Gelbaugh, Phillip J. Mercier, Jeremy Goldman, and Jaroslaw W. Drelich

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Preservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes, Vadim B. Fedorov, Anna V. Goropashnaya, Øivind Tøien, Nathan C. Stewart, Celia Chang, Haifang Wang, Jun Yan, Louise C. Showe, Michael K. Showe, Seth W. Donahue, and Brian M. Barnes

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Fabrication of biocompatible, vibrational magnetoelastic materials for controlling cellular adhesion, Hal Holmes, Ee Lim Tan, Keat Ghee Ong, and Rupak Rajachar

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The development of the circadian heart rate rhythm (CHR) in Asian infants, Toke Hoppenbrouwers, Flavia Oliveira, Stanislaus Sandarupa, Michael Khoo, Michael Neuman, and Rangasamy Ramanathan

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Analysis of heart rate variability for predicting cardiorespiratory events in infants, Aaron Lewicke, Michael Corwin, Michael Schuckers, Xueyan Xu, Michael R. Neuman, and Stephanie Schuckers

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Yellow-bellied Marmots (Marmota flaviventris) preserve bone strength and microstructure during hibernation, Samantha J. Wojda, Meghan E. McGee-Lawrence, Richard A. Gridley, Janene Auger, Hal L. Black, and Seth W. Donahue

Works from 2011

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Biomaterial guides for lymphatic endothelial cell alignment and migration, Echoe M. Bouta, Connor McCarthy, Alexander Keim, Han Bing Wang, Ryan J. Gilbert, and Jeremy Goldman

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Robust CNS regeneration after complete spinal cord transection using aligned poly-l-lactic acid microfibers, Andres Hurtado, Jared M. Cregg, Han B. Wang, Dane F. Wendell, Martin Oudega, Ryan J. Gilbert, and John W. McDonald

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Mussel-inspired adhesives and coatings, Bruce P. Lee, P. B. Messersmith, J. N. Israelachvili, and J. H. Waite

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A simplified in vivo approach for evaluating the bioabsorbable behavior of candidate stent materials, Daniel Pierson, Jacob Edick, Aaron Tauscher, Erin Pokorney, Patrick Bowen, Jesse Gelbaugh, Jaroslaw W. Drelich, Jeremy Goldman, and et. al.