The development of the circadian heart rate rhythm (CHR) in Asian infants
Document Type
Article
Publication Date
7-1-2012
Abstract
Objective: To test the hypothesis that term-born Asian infants, at reduced risk to die of Sudden Infant Death Syndrome (SIDS) exhibit a circadian heart rate rhythm (CHR) at a later age than non-Asian term infants. Method: Repeated overnight heart rate (HR) traces obtained with a battery-operated Polar S810i heart-rate monitor at home in 17 Asian Torajan infants in Indonesia, were compared with those of 52 non-Asian infants monitored as part of the Collaborative Home Infant Monitoring Evaluation (CHIME). HR was determined using a moving window averaging technique. A comparison of median HR during quiet sleep (QS) episodes (identified by minimum HR variability), established the presence of CHR. Results: Seventy three percent of non-Asian CHIME infants ≤ 7 weeks exhibited CHR compared to 45% of Asian Torajan infants. Between 8 and 12. weeks, 94% of non-Asian CHIME infants exhibited CHR, compared to 33% of Asian Torajan infants (p < 0.001). Forty seven and 56% of Asian Torajan infants exhibited the CHR at the age intervals of 16-20. weeks and 21-25. weeks respectively. Active wakefulness percentages as a function of the entire recording and median QS HR were not significantly different in the two groups. Conclusion: Despite the fact that Asian Torajan infants were on average a week older than non-Asian CHIME babies, between two and three months of age only one in three exhibited the CHR, compared to virtually all non-Asian CHIME infants. We speculate that the cause of this difference rests in the infants' environment rather than their genetic origin. © 2011 Elsevier Ltd.
Publication Title
Early Human Development
Recommended Citation
Hoppenbrouwers, T.,
Oliveira, F.,
Sandarupa, S.,
Khoo, M.,
Neuman, M.,
&
Ramanathan, R.
(2012).
The development of the circadian heart rate rhythm (CHR) in Asian infants.
Early Human Development,
88(7), 555-561.
http://doi.org/10.1016/j.earlhumdev.2011.12.031
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/6295