Title
Catechol redox reaction: reactive oxygen species generation, regulation, and biomedical applications
Document Type
Book Chapter
Publication Date
10-25-2017
Abstract
Reactive oxygen species (ROS) are a group of highly reactive molecules containing oxygen. ROS are generated endogenously in different physiological processes such as metabolic system and wound healing responses. The biological responses of ROS are highly dependent on its concentration in the biological system. Natural polyphenols and catechol-containing compounds (i.e., mussel adhesive proteins, melanin, and polyphenols) demonstrate both pro- and antioxidant properties. These redox activities can be tailored to be used in various clinical applications. Here, we review the physiological generation and regulation of ROS and their effects in biological system and summarize the unique features of phenolic compounds and their incorporation into biomaterials for various biomedical applications.
Publication Title
Advances in Bioinspired and Biomedical Materials Volume 1
Recommended Citation
Forooshani, P. K.,
Meng, H.,
&
Lee, B. P.
(2017).
Catechol redox reaction: reactive oxygen species generation, regulation, and biomedical applications.
Advances in Bioinspired and Biomedical Materials Volume 1,
1252(10), 179-196.
http://doi.org/10.1021/bk-2017-1252.ch010
Retrieved from: https://digitalcommons.mtu.edu/biomedical-fp/29
Publisher's Statement
Copyright © 2017 American Chemical Society
Publisher's version of record: http://pubs.acs.org/doi/full/10.1021/bk-2017-1252.ch010