Title
In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel
Document Type
Article
Publication Date
2-2016
Abstract
We present a simple microfluidic technique to in-situ photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v %), a high photoinitiator concentration (1.5 w/v %), and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.
Publication Title
Biomicrofluidics
Recommended Citation
Wang, S.,
Jeon, O.,
Shankles, P. G.,
Liu, Y.,
Alsberg, E.,
Retterer, S. T.,
Lee, B. P.,
&
Choi, C. K.
(2016).
In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel.
Biomicrofluidics.
http://doi.org/10.1063/1.4941339
Retrieved from: https://digitalcommons.mtu.edu/biomedical-fp/7
Publisher's Statement
© 2016 AIP Publishing LLC. Publisher's version of record: http://dx.doi.org/10.1063/1.4941339