Targeting TLR2 agonists as immunomodulators with broad antiviral activity

Document Type

Article

Publication Date

4-1-2026

Abstract

Toll-like receptor-2 (TLR2) serves as an innate immune sensor that recognizes specific viral proteins, thereby initiating signaling pathways that can either enhance antiviral host defenses or induce pathological inflammatory responses. In this forum, we discuss the role of TLR2 and its agonists in enhancing antiviral and vaccine-induced immune responses.

Publication Title

Trends in immunology

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