New rhodamine nitroxide based fluorescent probes for intracellular hydroxyl radical identification in living cells
Document Type
Article
Publication Date
1-6-2012
Abstract
The synthesis, characteristics, and biological applications of a series of new rhodamine nitroxide fluorescent probes that enable imaging of hydroxyl radicals (•OH) in living cells are described. These probes are highly selective for •OH in aqueous solution, avoiding interference from other reactive oxygen species (ROS), and they facilitate •OH imaging in biologically active samples. The robust nature of these probes (high specificity and selectivity, and facile synthesis) offer distinct advantages over previous methods for •OH detection. © 2011 American Chemical Society.
Publication Title
Organic Letters
Recommended Citation
Yapici, N.,
Jockusch, S.,
Moscatelli, A.,
Mandalapu, S.,
Itagaki, Y.,
Bates, D.,
Wiseman, S.,
Gibson, K.,
Turro, N.,
&
Bi, L.
(2012).
New rhodamine nitroxide based fluorescent probes for intracellular hydroxyl radical identification in living cells.
Organic Letters,
14(1), 50-53.
http://doi.org/10.1021/ol202816m
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/8197