Highly Asymmetric Heterogeneous Catalytic Hydrogenation of Isophorone on Proline Modified Base-supported Palladium Catalysts
Document Type
Article
Publication Date
3-10-2006
Department
Department of Chemistry
Abstract
A highly effective asymmetric heterogeneous catalytic hydrogenation of isophorone (3,5,5-trimethyl-2-cyclohexenone) by proline-modified base-supported Pd catalysts is described. Effective combination of enhanced proline adsorption and secondary kinetic resolution resulted in very high enantioselectivities (ee up to 99%). Using (S)- and (R)-proline enantiomers as chiral auxiliaries, both enantiomers of the product were obtained with excellent optical yields.
Publication Title
Journal of Catalysis
Recommended Citation
Mhadgut, S.,
Török, M.,
Esquibel, J.,
&
Török, B.
(2006).
Highly Asymmetric Heterogeneous Catalytic Hydrogenation of Isophorone on Proline Modified Base-supported Palladium Catalysts.
Journal of Catalysis,
238(2), 441-448.
http://doi.org/10.1016/j.jcat.2006.01.004
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/6624
Publisher's Statement
© 2006 Elsevier Inc. All rights reserved.