The structure of some methyl and benzyl malonate derivatives of pyrimidine

Document Type

Article

Publication Date

1-1-1980

Department

Department of Chemistry; Department of Chemical Engineering

Abstract

Reaction of 2,4,6‐trichloropyrimidine with sodium dibenzylmalonate in p‐dioxane gave 4,6‐dichloro‐2‐(dibenzylmalonyl)pyrimidine, while reaction of 2,4,6‐trichloropyrimidine with sodium dimethylmalonate yielded both 4,6‐dichloro‐2‐(dimethylmalonyl)pyrimidine and 2,2‐bis‐(4,6‐dichloropyrimidin‐2‐yl)dimethylmalonate. Structural studies using nmr, ir and uv spectroscopy indicate that for the former two compounds in basic solvent, an equilibrium exists between the keto forms and resonance‐stabilized enolate ions.

Publisher's Statement

Copyright © 1980 Journal of Heterocyclic Chemistry. Publisher’s version of record: https://doi.org/10.1002/jhet.5570170334

Publication Title

Journal of Heterocyclic Chemistry

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