Document Type
Article
Publication Date
3-2-2023
Department
Department of Cognitive and Learning Sciences
Abstract
This study: (a) compared executive functions between deficit (DS) and non-deficit schizophrenia (NDS) patients and healthy controls (HC), controlling premorbid IQ and level of education; (b) compared executive functions in DS and NDS patients, controlling premorbid IQ and psychopathological symptoms; and (c) estimated relationships between clinical factors, psychopathological symptoms, and executive functions using structural equation modelling. Participants were 29 DS patients, 44 NDS patients, and 39 HC. Executive functions were measured with the Mazes Subtest, Spatial Span Subtest, Letter Number Span Test, Color Trail Test, and Berg Card Sorting Test. Psychopathological symptoms were evaluated with the Positive and Negative Syndrome Scale, Brief Negative Symptom Scale, and Self-evaluation of Negative Symptoms. Compared to HC, both clinical groups performed poorer on cognitive flexibility, DS patients on verbal working memory, and NDS patients on planning. DS and NDS patients did not differ in executive functions, except planning, after controlling premorbid IQ and negative psychopathological symptoms. In DS patients, exacerbation had an effect on verbal working memory and cognitive planning; in NDS patients, positive symptoms had an effect on cognitive flexibility. Both DS and NDS patients presented deficits, affecting the former to a greater extent. Nonetheless, clinical variables appeared to significantly affect these deficits.
Publication Title
Journal of Clinical Medicine
Recommended Citation
Bielecki, M.,
Tyburski, E.,
Plichta, P.,
Mak, M.,
Kucharska-Mazur, J.,
Podwalski, P.,
Rek-Owodziń, K.,
Waszczuk, K.,
Sagan, L.,
Mueller, S.,
Michalczyk, A.,
Misiak, B.,
&
Samochowiec, J.
(2023).
Executive Functions and Psychopathology Dimensions in Deficit and Non-Deficit Schizophrenia.
Journal of Clinical Medicine,
12(5).
http://doi.org/10.3390/jcm12051998
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/16994
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Version
Publisher's PDF
Publisher's Statement
Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. Publisher’s version of record: https://doi.org/10.3390/jcm12051998