Near-infrared fluorescent probe based on rhodamine derivative for detection of NADH in live cells
Document Type
Article
Publication Date
1-1-2022
Department
Department of Chemistry
Abstract
A near-infrared fluorescent probe was prepared for selective detection of reduced nicotinamide adenine dinucleotide (NADH) in live cells. The probe turns off the fluorescence with a closed spironolactone switch. However, reduction of the probe by NADH turns on fluorescence at 740 nm. Theoretical calculations suggest a more planar arrangement between the rhodamine and quinoline moieties with increased π-delocalization resulting from reduction.
Publication Title
Methods
Recommended Citation
Zhang, Y.,
Arachchige, D.,
Olowolagba, A.,
Luck, R.,
&
Liu, H.
(2022).
Near-infrared fluorescent probe based on rhodamine derivative for detection of NADH in live cells.
Methods.
http://doi.org/10.1016/j.ymeth.2022.03.019
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/15946
