Production of a toxic shock syndrome toxin variant by Staphylococcus aureus strains associated with sheep, goats, and cows
Document Type
Article
Publication Date
1-1-1989
Abstract
A toxic shock syndrome toxin (TSST) variant with an isoelectric point (pI) of 8.6 produced by an ovine-associated Staphylococcus aureus strain was described previously. Analysis of additional strains associated with sheep, goats, cows, and humans by isoelectric focusing with immunoblotting using monoclonal antibodies revealed that all 18 strains associated with sheep and all 12 strains associated with goats produced the TSST variant. Only 1 of 10 bovine-associated strains and no human-associated strains produced the variant, whereas the others produced TSST-1 (pI between 7.0 and 7.2). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis with immunoblotting indicated that both TSST-1 and the TSST variant had a molecular size of 24 kilodaltons.
Publication Title
Journal of Clinical Microbiology
Recommended Citation
Ho, G.,
Campbell, W.,
Bergdoll, M.,
&
Carlson, E.
(1989).
Production of a toxic shock syndrome toxin variant by Staphylococcus aureus strains associated with sheep, goats, and cows.
Journal of Clinical Microbiology,
27(9), 1946-1948.
http://doi.org/10.1128/jcm.27.9.1946-1948.1989
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/12271