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Date of Award

2016

Document Type

Campus Access Master's Report

Degree Name

Master of Science in Biomedical Engineering (MS)

Administrative Home Department

Department of Biomedical Engineering

Advisor 1

Keat Ghee Ong

Committee Member 1

Megan C. Frost

Committee Member 2

Sean J. Kirkpatrick

Abstract

A standalone, reconfigurable, embedded wireless sensing device was developed for real-time measurement of multiple parameters such as forces/strains and temperature. While there are commercial sensor systems that can provide real-time monitoring, many of them are too large and consume too much power for certain research applications. The wireless sensor platform presented here is small in size (circuit size is about 3.0 cm × 1.5 cm × 0.50 cm), battery powered, and can be easily configured, making them ideal for use as a medical research tool. For example, in vivo physiological data can be collected by this sensor platform to validate results from simulations or in vitro experiments. As a proof of concept experiment, a device was designed and fabricated to monitor tensile and compressive forces, such as those experienced by an external fixation plate used to stabilize long bone fractures. Strain sensor measurements were validated against a commercial mechanical loading instrument for relevant loads that an animal (goat) would experience during in vivo testing (up to 250 N). The loader was configured to apply a maximum force of 250 N to the bone fixation plate at a rate of 4 kN/min. The results show the strain sensor is capable of sensing the load applied to the fixation apparatus with a force detection resolution of 2.7 N. The noise level in the system was 10 mV, which is 5% of the full scale output (200 mV) at a maximum load of 250N. Cyclic testing of the system showed optimal stability and no observable drift in the sensor.

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