Near-infrared fluorescent probes with large stokes shifts for sensing Zn(II) ions in living cells
Document Type
Article
Publication Date
11-17-2016
Abstract
We report two new near-infrared fluorescent probes based on Rhodol counterpart fluorophore platforms functionalized with dipicolylamine Zn(II)-binding groups. The combinations of the pendant amines and fluorophores provide the probes with an effective three-nitrogen-atom and one-oxygen-atom binding motif. The fluorescent probes with large Stokes shifts offer sensitive and selective florescent responses to Zn(II) ions over other metal ions, allowing a reversible monitoring of Zn(II) concentration changes in living cells, and detecting intracellular Zn(II) ions released from intracellular metalloproteins.
Publication Title
ACS Sensors
Recommended Citation
Zhang, S.,
Adhikari, R.,
Fang, M.,
Dorh, N.,
Li, C.,
Jaishi, M.,
Zhang, J.,
Tiwari, A.,
Pati, R.,
Luo, F.,
&
Liu, H.
(2016).
Near-infrared fluorescent probes with large stokes shifts for sensing Zn(II) ions in living cells.
ACS Sensors,
1(12), 1408-1415.
http://doi.org/10.1021/acssensors.6b00490
Retrieved from: https://digitalcommons.mtu.edu/chemistry-fp/102
Publisher's Statement
© 2016 American Chemical Society. Publisher's version of record: https://dx.doi.org/10.1021/acssensors.6b00490