Development of Polydopamine Coating on Biodegradable Zn Implant for Cardiovascular Stent Application

Document Type

Conference Proceeding

Publication Date

4-1-2026

Department

Department of Materials Science and Engineering; Department of Biomedical Engineering

Abstract

Bioactive polymer-metal ion coatings on biodegradable implants can significantly enhance biocompatibility and support vascular remodeling through controlled metal ion release. Mussel-inspired polydopamine (PDA) is a biocompatible polymer that forms strong bonds with metal surfaces using its catechol and amine groups. Its potential for secondary functionalization makes it ideal for creating bioactive coatings. In this study, PDA coatings loaded with copper ions (PDA-Cu) were applied to zinc (Zn) implants using an immersion method. The microstructure of the PDA-Cu coating revealed the deposition of spherical polydopamine particles on the substrate surface, measuring 150–160 nm in diameter, which indicates a homogeneous PDA-Cu coating on the Zn substrate. The PDA-Cu coatings were characterized using Fourier Transform Infrared (FTIR) spectroscopy and X-ray Photoelectron Spectroscopy (XPS), confirming uniform chemical bonding. The successful formation of a homogeneous PDA-Cu layer on Zn improved the corrosion resistance of the implants. Electrochemical tests showed that the corrosion rate decreased from approximately 0.8 to 0.3 mm/year after applying the PDA-Cu coating. This reduction in corrosion rate compared to bare zinc suggests enhanced degradation control, making it a promising option for implant applications.

Publication Title

Minerals Metals and Materials Series

ISBN

9783032138279

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