Improved synthesis of 2,5-anhydro-d-allononitrile
Document Type
Article
Publication Date
4-16-1983
Department
Department of Chemical Engineering; Department of Chemistry
Abstract
Two types of mixed ester of β-d-ribofuranose were synthesized. The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O-2, 3, and 5. The three esters obtained in the highest yields, starting from d-ribose, were then converted into the halides and nitriles. Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2,3,5-tri-O-p-toluyl-β-d-ribofuranose, which afforded 2,5-anhydro-3,4,6-tri-O-p-toluyl-d-allononitrile in 60% yield.
Publication Title
Carbohydrate Research
Recommended Citation
El Khadem, H.,
&
Kawai, J.
(1983).
Improved synthesis of 2,5-anhydro-d-allononitrile.
Carbohydrate Research,
115(C), 131-138.
http://doi.org/10.1016/0008-6215(83)88141-5
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/5215
