Document Type
Article
Publication Date
1-1-2014
Department
Department of Chemical Engineering
Abstract
Gold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate. The dextran sulfate coating changed the local refractive index, which was observed as a red shift in the longitudinal plasmon band. After the addition of 8 μM concanavalin-A, gold nanorod aggregates were formed as shown by TEM analysis. The corresponding UV-Vis spectrum peak wavelength showed a red shift from 701 nm of dextran sulfate coated gold nanorods to 718 nm of concanavalin-A promoted gold nanorod aggregates. The gold nanorod aggregates were dissociated when 12 mM glucose was introduced, as illustrated by TEM images. The longitudinal plasmon resonance of the UV-Vis spectrum also showed a blue shift from 718 nm of dextran sulfate-coated gold nanorods associated by concanavalin-A to 714 nm of dissociated dextran sulfate-coated gold nanorods. The degree of the spectrum peak wavelength shift of the dextran sulfate-coated gold nanorods associated by concanavalin-A can be modulated using glucose ranging from 1 to 30 mM.
Publication Title
Nanomaterials and Nanotechnology
Recommended Citation
Peng, C.,
&
Pachpinde, S.
(2014).
Longitudinal plasmonic detection of glucose using gold nanorods.
Nanomaterials and Nanotechnology,
4(1).
http://doi.org/10.5772/58530
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/3229
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
Version
Publisher's PDF
Publisher's Statement
© 2014 The Author(s). Publisher’s version of record: https://doi.org/10.5772/58530