Green Synthesis of Silver Nanoparticles Using Argyreia nervosa Leaf Extract and Their Antimicrobial Activity

Document Type

Article

Publication Date

4-2023

Department

Department of Physics

Abstract

The biogenic synthesis of silver nanoparticles (AgNPs) has attracted many researchers due to their physical, chemical, optical, and biological properties, embracing a range of activities such as antibacterial, antifungal, anti-inflammatory, and anticancer activities. The purpose of this work is to synthesize and characterize AgNPs using Argyreia nervosa (AN) plant leaf extract, as well as to test their antimicrobial applications. In this work, silver nitrate (AgNO3) at 0.1 mM concentration and stable AgNPs were synthesized and observed by monitoring the color change of the solution from light yellow to brown. The UV–Vis spectrum shows a peak at 445 nm, confirming the formation of AN-AgNPs and Fourier transform infrared (FTIR) results confirm the presence of chemical groups which act as reducing agents stabilizing the AN-AgNPs and antimicrobial capping agents enhancing antimicrobial properties of AN-AgNPs. The crystalline behavior of these AN-AgNPs is confirmed through X-ray powder diffraction (PXRD) peaks. The morphology of AN-AgNPs and their sizes were studied (sizes range from 10 to 40 nm) using scanning electron microscopy (SEM). The disk diffusion assay shows the antimicrobial activity over Escherichia coli pathogenic microorganisms of clinical interest. The obtained results confirm a more significant antimicrobial effect of the biogenic AN-AgNPs maintaining low cytotoxicity. This work presents a potential way to produce non-toxic biogenic AgNPs with enhanced antibacterial activity, which can meet the increasing global demand for biogenic AgNPs as an alternative to antibiotics.

Publication Title

Plasmonics

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