Document Type
Article
Publication Date
2-19-2021
Department
Department of Biomedical Engineering
Abstract
Mussel foot proteins (Mfps) contain a large amount of the catecholic amino acid, DOPA, allowing the marine organism to anchor themselves onto various surfaces in a turbulent and wet environment. Modification of polymers with catechol imparts these materials with a strong, wet adhesive property. The oxidation chemistry and oxidation state of catechol are critical to the design of synthetic adhesives and biomaterials. In this Mini-Review, the effect of catechol oxidation state on adhesion, oxidation-mediated catechol cross-linking, and the generation of reactive oxygen species (ROS) during catechol oxidation are reviewed. Finally, the tuning of catechol oxidation state in designing stimuli-responsive adhesives and the utilization of ROS byproducts for antimicrobial and antiviral applications are reviewed.
Publication Title
ACS Omega
Recommended Citation
Pinnataip, R.,
&
Lee, B.
(2021).
Oxidation Chemistry of Catechol Utilized in Designing Stimuli-Responsive Adhesives and Antipathogenic Biomaterials.
ACS Omega,
6(8), 5113-5118.
http://doi.org/10.1021/acsomega.1c00006
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/14814
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Version
Publisher's PDF
Publisher's Statement
© 2021 The Authors. Published by. American Chemical Society. Publisher’s version of record: https://doi.org/10.1021/acsomega.1c00006