"Integration of optical protein and quantum dot films for biosensing" by Mark Griep, Govind Mallick et al.
 

Integration of optical protein and quantum dot films for biosensing

Document Type

Conference Proceeding

Publication Date

11-10-2008

Abstract

The unique energy transfer interaction between the optical protein bacteriorhodopsin (bR) and CdSe/ZnS quantum dots (QDs) provides a potential modulation mechanism for bio-nano electronic application. We have utilized ionic-self assembled monolayer (I-SAM) techniques to create a novel alternating monolayer system of QDs and bR on a conductive ITO substrate. Results demonstrate the ability to efficiently create bR/QD multilayer films along with the ability to control bR/QD spacing on the nanometer scale. I-SAM films of this nature demonstrate a sharp decrease in QD emission when deposited in close proximity to bR, suggesting possible fluorescence resonance energy transfer (FRET) effects in a bR/QD nanoscale system. The ability to modulate the QD photonic output based on proximity to bR in the I-SAM films could provide a direct method to modulate the electrical output for bio-nano sensing applications. © 2008 IEEE.

Publication Title

2008 8th IEEE Conference on Nanotechnology, IEEE-NANO

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