Date of Award


Document Type

Open Access Master's Thesis

Degree Name

Master of Science in Biomedical Engineering (MS)

Administrative Home Department

Department of Biomedical Engineering

Advisor 1

Sean J Kirkpatrick

Committee Member 1

Jingfeng Jiang

Committee Member 2

Keat Ghee Ong


The mechanical properties of the skin are an indication of its physiological condition. The properties can serve as potential information for dermatologists for diagnosis and qualitative assessment. Elastography is a medical imaging modality developed to extract the elastic properties of a tissue by application of an external force. Optical elastography is a technique of elastography which uses laser speckle tracking to study the elastic properties of several soft tissue including skin.

This work is aimed at developing an optical elastography setup that can study the elastic properties of skin. The setup includes an imaging system and a force-application system controlled by a user-friendly Graphical User Interface(GUI). This thesis describes, in detail, the hardware and software components involved in the setup and also, the results obtained with the use of this setup.