Synthetic oligodeoxynucleotide purification by polymerization of failure sequences
Synthetic oligodeoxynucleotide is purified by capping failure sequences with an acrylated phosphoramiditefollowed by polymerization and product extraction. The method is suitable for large scale oligonucleotide drugpurification.
Fang, Shiyue; Fueangfung, Suntara; Lin, Xi; Zhang, Xiang; Mai, Wenpeng; Bi, Lanrong; and Green, Sarah A., "Synthetic oligodeoxynucleotide purification by polymerization of failure sequences" (2010). Department of Chemistry Publications. 86.