Date of Award

2017

Document Type

Open Access Master's Thesis

Degree Name

Master of Science in Biomedical Engineering (MS)

Administrative Home Department

Department of Biomedical Engineering

Advisor 1

Keat Ghee Ong

Committee Member 1

Bruce P. Lee

Committee Member 2

Smitha Rao

Abstract

It is has been proven that infection in the body cause a local temperature increase due to localized inflammation. Therefore, a method to provide early diagnostic or long-term tracking of this infection will provide great benefits to patients with diabetic foot ulcers or sickle cell disease, and those receiving hemodialysis where they suffer from a weakened immune system. The goal of this project is to develop an implantable wireless temperature sensor based on a wireless sensor network system for monitoring infections in situ. The analog signals from the thermistors are digitized and wirelessly transmitted to a computer with an ez430-rf2500 wireless sensor network (Texas Instruments). The sensor device is designed to monitor temperature at a fixation plate of a rodent under an infection model. Two prototypes of the system, T1 and T2, were designed and fabricated during this work. The sensors displayed good sensitivity, stability and reliability during the testing. The system was optimized for better timing accuracy to allow power management. Such a sensor could be used for long term monitoring of infections associated with orthopedic implants.

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