Optimization and Application of Laser-Induced Graphene Electrodes with Nickel Hydroxide Nanoparticles for Ultrasensitive Non-Enzymatic Glucose Sensing

Document Type

Article

Publication Date

12-17-2024

Department

Department of Biomedical Engineering; Department of Chemical Engineering

Abstract

This study optimizes laser-induced graphene (LIG) electrodes for electrochemical sensing by varying CO2 laser parameters (i.e., power, speed, PPI) to convert polyimide into graphene to achieve high electrochemical performance. The electrodes are further modified with electrodeposited nickel hydroxide (Ni(OH)₂) nanoparticles to catalyze glucose oxidation and sense glucose in a 0.1 M NaOH solution. Through detailed morphological and electrochemical characterization, we demonstrate that multiple laser passes significantly improve the LIG electrode's electrical conductivity, surface morphology, and electrochemical performance. As a demonstration, the real-time amperometric detection of glucose using LIG-Ni(OH)2 electrodes achieved an ultrahigh sensitivity of 2577 μA/cm2∙mM glucose. Our findings provide valuable insights into the fabrication of high-performance, cost-effective, and scalable electrochemical sensors using LIG electrodes.

Publication Title

2024 IEEE SENSORS

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