Title

The Alzheimer's Β amyloid (A Β1-39) monomer in an implicit solvent

Document Type

Article

Publication Date

5-8-2008

Abstract

Results from replica-exchange and regular room temperature molecular dynamics simulations of the Alzheimer's Β amyloid (A Β1-39) monomer in an implicit solvent are reported. Our data indicate that at room temperature, the monomer assumes random-coil and soluble conformations. No beta content is observed which therefore seems to be a product of oligomerization and aggregation of monomers. © 2008 American Institute of Physics.

Publication Title

Journal of Chemical Physics

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