A convenient synthesis of N-acylpyrroles from primary aromatic amides
Document Type
Article
Publication Date
1-1-2003
Abstract
Synthesis of N-acylpyrroles in 45-85% isolated yield from primary aromatic amides and excess 2,5-dimethoxytetrahydrofuran in presence of one equivalent of thionyl chloride is reported. This method has several advantages including short reaction times, mild reaction conditions, and easy workup. The technique works particularly well for deactivated aromatic amides.
Publication Title
Synthesis
Recommended Citation
Ekkati, A.,
&
Bates, D.
(2003).
A convenient synthesis of N-acylpyrroles from primary aromatic amides.
Synthesis(13), 1959-1961.
http://doi.org/10.1055/s-2003-41020
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/8646
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