pKa of Azatriptycene
The pKa of azatriptycene (9H-9,10(1′,2′)-benzenoacridine) (4) is measured and found to be 2.1. This value is obtained by potentiometric titration of 4 at 25° with HClO4 In anhydrous HOAc and is related to the aqueous system through the relationship of Wegmann and Simon. The inductive effect of adding benzo-substituents to 1 reduces the basicity an average of 2.8 pK units per substituent. © 1976, American Chemical Society. All rights reserved.
Journal of Chemical and Engineering Data
pKa of Azatriptycene.
Journal of Chemical and Engineering Data,
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