Synthesis of cyclic allyl vinyl ethers using Pt(II)-catalyzed isomerization of oxo-alkynes
Several alkynyl epoxides and one alkynyl allyl alcohol were isomerized to cyclic allyl vinyl ethers (3,4-dihydro-2H-1,4-oxazines) using PtCl2 as the catalyst. Three of these allyl vinyl ethers were converted to 2-hydroxymorpholine derivatives by hydrolysis and two were converted to piperidine derivatives by thermal Claisen rearrangement. © 2009 Elsevier Ltd. All rights reserved.
Synthesis of cyclic allyl vinyl ethers using Pt(II)-catalyzed isomerization of oxo-alkynes.
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