Title

Ditopic ligands featuring [P,S], [P,P] or [P,B] chelating pockets housed on a protected o-hydroquinone core

Document Type

Article

Publication Date

1-15-2013

Abstract

1,2-Dibromo-4,5-dimethoxybenzene was explored as a platform for the buildup of ditopic ligands. Low temperature reactions with n-butyllithium followed by quenches with various electrophiles led to the syntheses (2-bromo-4,5- dimethoxyphenyl)diphenylphosphine (1), (4,5-dimethoxy-2-(methylthio)phenyl) diphenylphosphine (2), 1,2-bis(diphenylphosphino)-4,5-dimethoxybenzene (3), and (2-(dicyclohexylboryl)-4,5-dimethoxyphenyl)diphenylphosphine (4). Oxidation of 3 produced 1,2-bis(diphenylphosphoryl)-4,5-dimethoxybenzene (5). All compounds were characterized by multinuclear (1H/13C/ 31P{1H}) NMR spectroscopy and by high resolution mass spectrometry. In addition, single crystal X-ray diffraction characterizations of 1, 3, 4, and 5 were also carried out. Reactivity of o-phosphinophenylborane 4 toward molecular hydrogen was also probed. © 2012 Elsevier B.V. All rights reserved.

Publication Title

Journal of Organometallic Chemistry

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