Synthesis of 2‐(o‐chloropheny)‐ and 2‐(2′,6′‐dichlorophenyl)‐4‐formyl‐1,2,3‐triazoles
Mesoaldehyde 1,3‐dioxime was treated with either o‐chlorophenyl‐ or 2,6 dichloro‐phenylhydrazine to give the corresponding 2‐chlorophenylhydrazone. Hydrazones 1a and 1b were treated with acetic anhydride and cyclized to triazoles (3a and 6a) with cesium carbonate. These were then hydrolized to the previously unknown chlorophenyltriazole aldehydes (4a and 4b). They were also converted to a number of acid derivatives, alcohols, and amines. Copyright © 1979 Journal of Heterocyclic Chemistry
Journal of Heterocyclic Chemistry
El Khadem, H.
Synthesis of 2‐(o‐chloropheny)‐ and 2‐(2′,6′‐dichlorophenyl)‐4‐formyl‐1,2,3‐triazoles.
Journal of Heterocyclic Chemistry,
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