Synthesis of 2‐(o‐chloropheny)‐ and 2‐(2′,6′‐dichlorophenyl)‐4‐formyl‐1,2,3‐triazoles
Document Type
Article
Publication Date
1-1-1979
Department
Department of Chemistry; Department of Chemical Engineering
Abstract
Mesoaldehyde 1,3‐dioxime was treated with either o‐chlorophenyl‐ or 2,6 dichloro‐phenylhydrazine to give the corresponding 2‐chlorophenylhydrazone. Hydrazones 1a and 1b were treated with acetic anhydride and cyclized to triazoles (3a and 6a) with cesium carbonate. These were then hydrolized to the previously unknown chlorophenyltriazole aldehydes (4a and 4b). They were also converted to a number of acid derivatives, alcohols, and amines.
Publication Title
Journal of Heterocyclic Chemistry
Recommended Citation
Swartz, D.,
&
El Khadem, H.
(1979).
Synthesis of 2‐(o‐chloropheny)‐ and 2‐(2′,6′‐dichlorophenyl)‐4‐formyl‐1,2,3‐triazoles.
Journal of Heterocyclic Chemistry,
16(5), 909-912.
http://doi.org/10.1002/jhet.5570160515
Retrieved from: https://digitalcommons.mtu.edu/michigantech-p/3741
Publisher's Statement
Copyright © 1979 Journal of Heterocyclic Chemistry. Publisher’s version of record: https://doi.org/10.1002/jhet.5570160515