Multifunctional Polymeric Micelles for Drug Delivery and Therapeutics

Document Type

Book Chapter

Publication Date

1-22-2013

Department

Department of Chemical Engineering

Abstract

Cancer therapy is quickly moving towards the design of novel and target drugs. However, one of the major obstacles to successful clinical treatment is the development of safe and effective drug delivery systems without harming the surrounding normal cells. In recent years, polymeric micelles have been the focus of much interest as alternative vehicles for the solubilization of poorly water-soluble molecules, rendering clear advantages over current solubilizing agents in drug delivery. The self-assembled polymeric micelles for drug delivery and therapeutics are composed of a hydrophobic inner core and a hydrophilic outer shell. To specifically target cancer cells, polymeric micellar nanoparticles are tagged with functional moieties. The purpose of this review is to provide an update on the current status of multifunctional polymeric micelles for drug delivery and therapeutics.

Publisher's Statement

© 2013 Scrivener Publishing LLC. Publisher’s version of record: https://doi.org/10.1002/9781118636299.ch15

Publication Title

Nanomedicine for Drug Delivery and Therapeutics

ISBN

9781118414095

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