Dioxygen Binding Is Controlled by the Protein Environment in Non-heme Fe^II and 2-Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene-Forming Enzyme, Shobhit Chaturvedi, Midhun George Thomas, Simahudeen Bathir Jaber Sathik Rifayee, Walter White, Jon Wildey, Cait Warner, Christopher J. Schofield, Jian Hu, Robert P. Hausinger, Tatyana Karabencheva-Christova, Christo Christov
Michigan Tech Publications

Can Second Coordination Sphere and Long-Range Interactions Modulate Hydrogen Atom Transfer in a Non-Heme Fe(II)-Dependent Histone Demethylase?, Shobhit Chaturvedi, Simahudeen Bathir Jaber Sathik Rifayee, Sodiq Waheed, Jon Wildey, Cait Warner, Christopher J. Schofield, Tatyana Karabencheva-Christova, Christo Christov
Michigan Tech Publications

How Human TET2 Enzyme Catalyzes the Oxidation of Unnatural Cytosine Modifications in Double-Stranded DNA, Sodiq Waheed, Ann Varghese, Shobhit Chaturvedi, Tatyana Karabencheva-Christova, Christo Christov
Michigan Tech Publications

Effects of the Nature of Metal Ion, Protein and Substrate on the Catalytic Center in Matrix Metalloproteinase-1: Insights from Multilevel MD, QM/MM and QM Studies, Ann Varghese, Shobhit Chaturvedi, Bella DiCastri, Emerald Mehler, Gregg B. Fields, Tatyana G. Karabencheva-Christova
Michigan Tech Publications

Effects of the Nature of the Metal Ion, Protein and Substrate on the Catalytic Center in Matrix Metalloproteinase-1: Insights from Multilevel MD, QM/MM and QM Studies, Ann Varghese, Shobhit Chaturvedi, Bella DiCastri, Emerald Mehler, Gregg B. Fields, Tatyana Karabencheva-Christova
Michigan Tech Publications

A synergy between the catalytic and structural Zn(II) ions and the enzyme and substrate dynamics underlies the structure–function relationships of matrix metalloproteinase collagenolysis, Ann Varghese, Shobhit Chaturvedi, Gregg B. Fields, Tatyana Karabencheva-Christova
Michigan Tech Publications

Catalytic Mechanism of Human Ten-Eleven Translocation-2 (TET2) Enzyme: Effects of Conformational Changes, Electric Field, and Mutations, Sodiq Waheed, Shobhit Chaturvedi, Tatyana Karabencheva-Christova, Christo Z. Christov
Michigan Tech Publications

Atomic and electronic structure determinants distinguish between ethylene formation and L-arginine hydroxylation reaction mechanisms in the ethylene-forming enzyme, Christo Z. Christov, Shobhit Chaturvedi, Rajeev Ramanan, Jian Hu, Robert P. Hausinger
Michigan Tech Publications

Catalysis by the JmjC histone demethylase KDM4A integrates substrate dynamics, correlated motions and molecular orbital control, Rajeev Ramanan, Shobhit Chaturvedi, Nicolai Lehnert, Christopher J. Schofield, Tatyana Karabencheva-Christova, Christo Z. Christov
Michigan Tech Publications

Role of structural dynamics in selectivity and mechanism of non-heme Fe(II) and 2-Oxoglutarate-dependent Oxygenases involved in DNA repair, Sodiq Waheed, Rajeev Ramanan, Shobhit Chaturvedi, Nicolai Lehnert, Christopher J. Schofield, Christo Z. Christov, Tatyana Karabencheva-Christova
Michigan Tech Publications

Catalysis by the non-heme iron(II) histone demethylase PHF8 involves iron center rearrangement and conformational modulation of substrate orientation, Shobhit Chaturvedi, Rajeev Ramanan, Nicolai Lehnert, Christopher J. Schofield, Tatyana Karabencheva-Christova, Christo Z. Christov
Michigan Tech Publications

Conformational and Mechanistic Studies of AlkB and AlkBH2 DNA Demethylases, Tatyana Karabencheva-Christova, Sodic Waheed, Shobhit Chaturvedi, Rajeev Ramanan, Christo Christov
Michigan Tech Publications

Dynamics and Catalytic Mechanism of Histone Demethylase PHF8, Christo Christov, Shobhit Chaturvedi, Rajeev Ramanan, Tatyana Karabencheva-Christova
Michigan Tech Publications

Conformational dynamics underlies different functions of human KDM7 histone demethylases, Shobhit Chaturvedi, Rajeev Ramanan, Sodiq Waheed
Department of Chemistry Publications

Structure-function relationships in KDM7 histone demethylases., Shobhit Chaturvedi, Rajeev Ramanan, Sodiq Waheed, Tatyana Karabencheva-Christova, Christo Christov
Michigan Tech Publications

Integrating molecular probes and molecular dynamics to reveal binding modes of GLUT5 activatory and inhibitory ligands, Jon Ainsley, Shobhit Chaturvedi, Tatyana Karabencheva-Christova, Marina Tanasova, Christo Z. Christov
Michigan Tech Publications