Explore a selection of works produced by faculty in the Department of Biomedical Engineering at Michigan Technological University.

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Works from 2023

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Computational Modeling to Guide Structural Heart Interventions: Measure Twice (or Thrice) But Cut Once, Mohamad Alkhouli, Hoda Hatoum, and Nicolo Piazza

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Effect of Beta Blockers on the Hemodynamics and Thrombotic Risk of Coronary Artery Aneurysms in Kawasaki Disease, Alireza Asadbeygi, Simon Lee, John Kovalchin, and Hoda Hatoum

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Advances in Gelatin Bioinks to Optimize Bioprinted Cell Functions, Saad Asim, Tanveer A. Tabish, Usman Liaqat, Ibrahim T. Ozbolat, and Muhammad Rizwan

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Electrochemical Deactivation of Switchable Catechol-Containing Smart Adhesive from Nonconductive Surfaces, Md Saleh Akram Bhuiyan, James Manuel, Seyedehfatemeh Razaviamri, and Bruce Lee

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Fibroblast-Generated Extracellular Matrix Guides Anastomosis during Wound Healing in an Engineered Lymphatic Skin Flap, Alvis Chiu, Wenkai Jia, Yumeng Sun, Jeremy Goldman, and Feng Zhao

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Mechanical Properties and Morphological Alterations in Fiber-Based Scaffolds Affecting Tissue Engineering Outcomes, James Dolgin, Samerender Nagam Hanumantharao, Stephen Farias, Carl G. Simon, and Smitha Rao

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The impact of local blood residence time in neo-sinus on post transcatheter aortic valve replacement subclinical leaflet thrombosis-a commentary., Fateme Esmailie, Hoda Hatoum, Vinod H Thourani, and Lakshmi Prasad Dasi

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Anti-Inflammatory and Anti-Thrombogenic Properties of Arterial Elastic Laminae, Jeremy Goldman, Shu Q. Liu, and Brandon J. Tefft

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An Assessment of Blood Vessel Remodeling of Nanofibrous Poly(ε-Caprolactone) Vascular Grafts in a Rat Animal Model, Jana Horakova, Tereza Blassova, Zbynek Tonar, Connor McCarthy, Katerina Strnadova, David Lukas, Petr Mikes, Patrick Bowen, Roger J. Guillory II, Megan C. Frost, and Jeremy Goldman

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Editorial: Cell and therapeutic delivery using injectable hydrogels for tissue engineering applications, Ghulam Jalani, Muhammad Rizwan, Muhammad Aftab Akram, and Mohammad Mujahid

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Biodegradable magnesium materials regulate ROS-RNS balance in pro-inflammatory macrophage environment, Maria Paula Kwesiga, Amani A. Gillette, Seyedehfatemeh Razaviamri, Margaret E. Plank, Alexia L. Canull, Zachary Alesch, Weilue He, Bruce Lee, and Roger J. Guillory II

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Acrylate monomer polymerization triggered by iron oxide magnetic nanoparticles and catechol containing microgels, Bo Liu, Zhongtian Zhang, Bingqian Li, Qingping Liu, and Bruce Lee

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Conventional Platinum Metal Implants Provoke Restenosis Responses in Atherogenic but Not Healthy Arteries, Lea M. Morath, Roger J. Guillory II, Alexander A. Oliver, Shu Q. Liu, Martin L. Bocks, Galit Katarivas Levy, Jaroslaw Drelich, and Jeremy Goldman

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An attention residual u-net with differential preprocessing and geometric postprocessing: Learning how to segment vasculature including intracranial aneurysms, Nan Mu, Zonghan Lyu, Mostafa Rezaeitaleshmahalleh, Jinshan Tang, and Jingfeng Jiang

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An attention residual u-net with differential preprocessing and geometric postprocessing: Learning how to segment vasculature including intracranial aneurysms, Nan Mu, Zonghan Lyu, Mostafa Rezaeitaleshmahalleh, Jinshan Tang, and Jingfeng Jiang

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Automatic segmentation of abdominal aortic aneurysms from CT angiography using a context-aware cascaded U-Net, Nan Mu, Zonghan Lyu, Mostafa Rezaeitaleshmahalleh, Xiaoming Zhang, Todd Rasmussen, Robert McBane, and Jingfeng Jiang

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Can we explain machine learning-based prediction for rupture status assessments of intracranial aneurysms?, Nan Mu, M. Rezaeitaleshmahalleh, Z. Lyu, M. Wang, J. Tang, C. M. Strother, J. J. Gemmete, A. S. Pandey, and J. Jiang

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Dynamic 3D imaging of contrast medium flow on an interventional C-arm using a pulsed injection protocol, Erick L. Oberstar, Martin G. Wagner, Mariya S. Pravdivtseva, Jingfeng Jiang, and Michael A. Speidel

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Benchtop proof of concept and comparison of iron- and magnesium-based bioresorbable flow diverters, Alexander A. Oliver, Cem Bilgin, Andrew J. Vercnocke, Kent D. Carlson, Ramanathan Kadirvel, Roger J. Guillory, Adam J. Griebel, Jeremy E. Schaffer, Dan Dragomir-Daescu, and David F. Kallmes

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Using Convolutional Neural Network-Based Segmentation For Image-Based Computational Fluid Dynamics Simulations Of Brain Aneurysms: Initial Experience In Automated Model Creation, Mostafa Rezaeitaleshmahalleh, Zonghan Lyu, Nan Mu, and Jingfeng Jiang

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Radiomic-based Textural Analysis of Intraluminal Thrombus in Aortic Abdominal Aneurysms: A Demonstration of Automated Workflow, Mostafa Rezaeitaleshmahalleh, Nan Mu, Zonghan Lyu, Weihua Zhou, Xiaoming Zhang, Todd E. Rasmussen, Robert D. McBane, and Jingfeng Jiang

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Radiomic-based Textural Analysis of Intraluminal Thrombus in Aortic Abdominal Aneurysms: A Demonstration of Automated Workflow, Mostafa Rezaeitaleshmahalleh, Nan Mu, Zonghan Lyu, Weihua Zhou, Xiaoming Zhang, Todd E. Rasmussen, Robert D. McBane, and Jingfeng Jiang

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Computerized Differentiation of Growth Status for Abdominal Aortic Aneurysms: A Feasibility Study, Mostafa Rezaeitaleshmahalleh, Kevin Sunderland, Zonghan Lyu, Tonie Johnson, Kristin King, David A. Liedl, Janet M. Hofer, Min Wang, Xiaoming Zhang, Wiktoria Kuczmik, Todd E. Rasmussen, Robert D. McBane, and Jingfeng Jiang

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Effect of aortic curvature on bioprosthetic aortic valve performance, Brennan Vogl, Rajat Gadhave, Zhenyu Wang, Ahmed El Shaer, Alejandra Chavez Ponce, Mohamad Alkhouli, and Hoda Hatoum

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Convolutional Neural Network-based Speckle Tracking for Ultrasound Strain Elastography: An Unsupervised Learning Approach, Shuojie Wen, Bo Peng, Xingyue Wei, Jianwen Luo, and Jingfeng Jiang

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A new method incorporating deep learning with shape priors for left ventricular segmentation in myocardial perfusion SPECT images, Fubao Zhu, Longxi Li, Jinyu Zhao, Chen Zhao, Shaojie Tang, Jiaofen Nan, Yanting Li, Zhongqiang Zhao, Jianzhou Shi, Zenghong Chen, Chuang Han, Zhixin Jiang, and Weihua Zhou

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Neuromorphic Computing: A Path to Artificial Intelligence Through Emulating Human Brains, Noah Zins, Yan Zhang, Chunxiu Yu, and Hongyu An

Works from 2022

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Predicting hemodynamic indices in coronary artery aneurysms using response surface method: An application in Kawasaki disease, Alireza Asadbeygi, Simon Lee, John Kovalchin, and Hoda Hatoum

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TCT-174 Comparison of Thrombotic Risk Between Coronary Artery Aneurysm and Coronary Ectasia Based on Hemodynamic Parameters, Alireza Asadbeygi, Simon Lee, John Kovalchin, and Hoda Hatoum

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Stress Corrosion Analysis and Direct Cell Viability of Biodegradable Zn-Fe-Ca Alloy in In-Vitro Conditions, Orit Avior, Noa Ben Ghedalia-Peled, Tomer Ron, Jeremy Goldman, Razi Vago, and Eli Aghion

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33 - Mitochondrial zinc toxicity, Olivia R. M. Bagshaw, Ricardo Alva, Jeremy Goldman, Jaroslaw W Drelich, and Jeffrey A. Stuart

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Catechol-functionalized sulfobetaine polymer for uniform zwitterionization via pH transition approach, Hoang Linh Bui, Sheng Di Huang, Bruce Lee, Ming Ying Lan, and Chun Jen Huang

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Subcellular Force Quantification of Endothelial Cells Using Silicone Pillar Arrays, Mohanish K. Chandurkar and Sangyoon J. Han

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Pay "Attention" to Adverse Weather: Weather-aware Attention-based Object Detection, Saket S. Chaturvedi, Lan Zhang, and Xiaoyong Yuan

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Bioresorbable vascular metallic scaffolds: Current status and research trends, Jaroslaw Drelich and Jeremy Goldman

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Thermomagnetic-Responsive Self-Folding Microgrippers for Improving Minimally Invasive Surgical Techniques and Biopsies, Caleigh R. Dunn, Bruce Lee, and Rupak Rajachar

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Patient-specific cardiovascular superelastic NiTi stents produced by laser powder bed fusion, Valentina Finazzi, Francesca Berti, Roger J. Guillory II, Lorenza Petrini, Barbara Previtali, and Ali Gökhan Demir

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Electrochemical Behaviour and Direct Cell Viability Analysis of Hybrid Implants Made of Ti-6Al-4V Lattices Infiltrated with a Bioabsorbable Zn-Based Alloy, Noa Gabay Bass, Galit Katarivas Levy, Tomer Ron, Razi Vago, Jeremy Goldman, Amnon Shirizly, and Eli Aghion

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Effects of MitraClip Therapy on Mitral Flow Patterns and Vortex Formation: An In Vitro Study, Shelley Chee Mei Gooden, Hoda Hatoum, Konstantinos Dean Boudoulas, Mani A. Vannan, and Lakshmi P. Dasi

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Improved Biocompatibility of Zn-Ag-based Stent Materials by Microstructure Refinement, Roger J. Guillory II, Ehsan Mostaed, Alexander A. Oliver, Lea M. Morath, Elisha Earley, Katie L. Flom, Timothy M. Kolesar, Ali Mostaed, Maria Paula Kwesiga, Jaroslaw Drelich, Kent D. Carlson, Dan Dragomir-Daescu, and Jeremy Goldman

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Flow dynamics of surgical and transcatheter aortic valves: Past to present, Hoda Hatoum, Sunyoung Ahn, Scott Lilly, Pablo Maureira, Juan Crestanello, Vinod H. Thourani, and Lakshmi Prasad Dasi

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Comparison of performance of self-expanding and balloon-expandable transcatheter aortic valves, Hoda Hatoum, Milad Samaee, Janarthanan Sathananthan, Stephanie Sellers, Maximilian Kuetting, Scott M. Lilly, Abdul R. Ihdayhid, Philipp Blanke, Jonathon Leipsic, Vinod H. Thourani, and Lakshmi Prasad Dasi

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Fabrication of a Completely Biological and Anisotropic Human Mesenchymal Stem Cell-Based Vascular Graft, Weilue He, Dhavan Sharma, Wenkai Jia, and Feng Zhao

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Enhancement of Lymphangiogenesis by Human Mesenchymal Stem Cell Sheet, Wenkai Jia, Weilue He, Guifang Wang, Jeremy Goldman, and Feng Zhao

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Beta Oscillation Detector Design for Closed-Loop Deep Brain Stimulation of Parkinson's Disease with Memristive Spiking Neural Networks, Zachary Kerman, Chunxiu Yu, and Hongyu An

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Multifunctional and Smart Tissue Adhesives for Biomedical Applications, Bruce Lee

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pH responsive antibacterial hydrogel utilizing catechol–boronate complexation chemistry, Bo Liu, Jianghua Li, Zhongtian Zhang, James D. Roland, and Bruce Lee

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Quantitative analysis of the impact of disorder on the structural and electrical properties of polymer fibers, R. A. Makin, S. N. Hanumantharao, S. Rao, and S. M. Durbin

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Overcoming supply disruptions during pandemics by utilizing found hardware for open source gentle ventilation, S. Oberloier, N. Gallup, and J. M. Pearce

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Benchtop Proof of Concept and Comparison of Iron- and Magnesium-Based Bioresorbable Flow Diverters, Alexander A. Oliver, Cem Bilgin, Andrew J. Vercnocke, Kent D. Carlson, Ramanathan Kadirvel, Roger J. Guillory, Adam J. Griebel, Jeremy E. Schaffer, Dan Dragomir-Daescu, and David F. Kallmes

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Bioresorbable flow diverters for the treatment of intracranial aneurysms: review of current literature and future directions, Alexander A. Oliver, Kent D. Carlson, Cem Bilgin, Jorge L. Arturo Larco, Ramanathan Kadirvel, Roger J. Guillory II, Dan Dragomir Daescu, and David F. Kallmes

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Multifunctional Cellular Targeting, Molecular Delivery, and Imaging by Integrated Mesoporous-Silica with Optical Nanocrescent Antenna: MONA, Younggeun Park, Hyeun Joong Yoon, Somin Eunice Lee, and Luke P. Lee

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Novel Stimuli-Responsive Pectin-PVP-Functionalized Clay Based Smart Hydrogels for Drug Delivery and Controlled Release Application, Shabnam Rehmat, Nayab Batool Rizvi, Saba Urooge Khan, Abdul Ghaffar, Atif Islam, Rafi Ullah Khan, Azra Mehmood, Hira Butt, and Muhammad Rizwan

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Antimicrobial Mechanisms of Biomaterials: From Macro to Nano, Shounak Roy, Sanchita Sarkhel, Deepali Bisht, Samerender Nagam Hanumantharao, Smitha Rao, and Amit Jaiswal

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Gradient and pressure recovery of a self-expandable transcatheter aortic valve depends on ascending aorta size: In vitro study, Milad Samaee, Hoda Hatoum, Michael Biersmith, Breandan Yeats, Shelley C. Gooden, Vinod H. Thourani, Rebecca T. Hahn, Scott Lilly, Ajit Yoganathan, and Lakshmi Prasad Dasi

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Graphene Oxide Functionalized Biosensor for Detection of Stress-Related Biomarkers, Erican Santiago, Shailu Shree Poudyal, Sung Y. Shin, and Hyeun Joong Yoon

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Non-antibiotic antimicrobial polydopamine surface coating to prevent stable biofilm formation on satellite telemetry tags used in cetacean conservation applications, Ariana Smies, Jeremy Wales, Maureen Hennenfent, Laura Lyons, Caleigh R. Dunn, Jooke Robbins, Bruce Lee, Alexandre Zerbini, and Rupak Rajachar

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Impact of spatial and temporal stability of flow vortices on vascular endothelial cells, Kevin Sunderland, Wenkai Jia, Weilue He, Jingfeng Jiang, and Feng Zhao

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Computational Assessment of Hemodynamics Vortices Within the Cerebral Vasculature Using Informational Entropy, Kevin Sunderland, Feng Zhao, and Jingfeng Jiang

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A Preliminary Study on the Usage of a Data-Driven Probabilistic Approach to Predict Valve Performance Under Different Physiological Conditions, Brennan Vogl, Yousef M. Darestani, Juan A. Crestanello, Brian R. Lindman, Mohamad A. Alkhouli, and Hoda Hatoum

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Flow dynamics in the sinus and downstream of third and fourth generation balloon expandable transcatheter aortic valves, Brennan Vogl, Ahmed El Shaer, Juan A. Crestanello, Mohamad Alkhouli, and Hoda Hatoum

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TCT-380 Predicting Device-Related Thrombosis Using Computational Fluid Dynamics, Brennan Vogl, Ahmed El Shaer, Alejandra Chavez Ponce, Alessandra Bavo, Matthieu De Beule, Mohamad Alkhouli, and Hoda Hatoum

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Effect of catheter ablation on the hemodynamics of the left atrium : Hemodynamics of ablation, Brennan Vogl, Ahmed El Shaer, Martin Van Zyl, Ammar M. Killu, Mohamad Alkhouli, and Hoda Hatoum

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EWI2 promotes endolysosome-mediated turnover of growth factor receptors and integrins to suppress lung cancer, Jie Wang, Jonathan D. Wren, Yingjun Ding, Junxiong Chen, Nikhil Mittal, Chao Xu, Xing Li, Cengxi Zeng, Meng Wang, Jing Shi, Yanhui H. Zhang, Sangyoon J. Han, and Xin A. Zhang

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Controlling the Flow Separation in Heart Valves Using Vortex Generators, Zhenyu Wang, Lakshmi Prasad Dasi, and Hoda Hatoum

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In-vitro cell culture model to determine toxic effects of soil Arsenic due to direct dermal exposure, Manas Warke, Madeline English, Laura De Marchi, Rohan Deep Sarkar, Srinivas Kannan, Rupali Datta, and Smitha Rao

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Striatal mechanisms of turning behaviour following unilateral dopamine depletion in mice, Chunxiu Yu, Tony Tianlun Jiang, Charles T. Shoemaker, David Fan, Mark A. Rossi, and Henry H. Yin

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A Deep Learning-based Method to Extract Lumen and Media-Adventitia in Intravascular Ultrasound Images, Fubao Zhu, Zhengyuan Gao, Chen Zhao, Hanlei Zhu, Jiaofen Nan, Yanhui Tian, Yong Dong, Jingfeng Jiang, Xiaohong Feng, Neng Dai, and Weihua Zhou

Works from 2021

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Bioabsorbable metal zinc differentially affects mitochondria in vascular endothelial and smooth muscle cells, Olivia R. M. Bagshaw, Fereshteh Moradi, Christopher S. Moffatt, Hillary A. Hettwer, Ping Liang, Jeremy Goldman, Jaroslaw Drelich, and Jeffrey A. Stuart

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3-D printed soft magnetic helical coil actuators of iron oxide embedded polydimethylsiloxane, Rasoul Bayaniahangar, Shahab Bayani Ahangar, Zhongtian Zhang, Bruce P. Lee, and Joshua M. Pearce

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Black Dots: Microcontact-Printed, Reference-Free Traction Force Microscopy, Kevin M. Beussman, Molly Y. Mollica, Andrea Leonard, Jeffrey Miles, John Hocter, Zizhen Song, Sangyoon J. Han, and et. al.

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Effect of Conductivity on In Situ Deactivation of Catechol-Boronate Complexation-Based Reversible Smart Adhesive, Md Saleh Bhuiyan, Bo Liu, James Manuel, Bin Zhao, and Bruce P. Lee

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GAN-segNet: A deep generative adversarial segmentation network for brain tumor semantic segmentation, Shaoguo Cui, Mingjun Wei, Chang Liu, and Jingfeng Jiang

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Morning sympathetic activity after evening binge alcohol consumption, Ian M. Greenlund, Hannah Cunningham, Anne L. Tikkanen, Jeremy A. Bigalke, Carl Smoot, John J. Durocher, and Jason R. Carter

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Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation, Sangyoon J. Han, Evgenia V. Azarova, Austin J. Whitewood, Alexia Bachir, Edgar Guttierrez, Alex Groisman, Alan R. Horwitz, Benjamin T. Goult, Kevin M. Dean, and Gaudenz Danuser

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Atrial and ventricular flows across a transcatheter mitral valve, Hoda Hatoum, Gunnar Askegaard, Ramji Iyer, and Lakshmi Prasad Dasi

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Predicting leaflet thrombosis: Is the clue in the blood?, Hoda Hatoum, Vinod H. Thourani, and Lakshmi Prasad Dasi

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Engineering the Lymphatic Network: A Solution to Lymphedema, Wenkai Jia, Hannah Hitchcock-Szilagyi, Weilue He, Jeremy Goldman, and Feng Zhao

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Preservation of microvascular integrity and immunomodulatory property of prevascularized human mesenchymal stem cell sheets, Wenkai Jia, Dhavan Sharma, Weilue He, Qi Xing, and Feng Zhao

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Additive manufacturing of conductive and high-strength epoxy-nanoclay-carbon nanotube composites, Masoud Kasraie and Parisa Pour Shahid Saeed Abadi

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Analysis of Human Gait Using Hybrid EEG-fNIRS-Based BCI System: A Review, Haroon Khan, Noman Naseer, Anis Yazidi, Per Kristian Eide, Hafiz Wajahat Hassan, and Peyman Mirtaheri

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Characterizing mechanical properties of soft tissues using non-contact displacement measurements: How should we assess the uncertainty?, Ami Kling, Sean J. Kirkpatrick, and Jingfeng Jiang

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Climbing robots in a sticky situation, Bruce Lee

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3D printing in cardiology: A review of applications and roles for advanced cardiac imaging, Ellen M. Lindquist, Jordan M. Gosnell, Sana K. Khan, John L. Byl, Weihua Zhou, Jingfeng Jiang, and et. al.

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Hepatic cell mobilization for protection against ischemic myocardial injury, Shu Q. Liu, John B. Troy, Chi Hao Luan, and Roger J. Guillory II

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Electroactive polymeric composites to mimic the electromechanical properties of myocardium in cardiac tissue repair, Kaylee Meyers, Bruce Lee, and Rupak Rajachar

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High-Resolution, Highly-Integrated Traction Force Microscopy Software, Nikhil Mittal and Sangyoon J. Han

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Progressive global perception and local polishing network for lung infection segmentation of COVID-19 CT images, Nan Mu, Hongyu Wang, Yu Zhang, Jingfeng Jiang, and Jinshan Tang

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Recent advances and directions in the development of bioresorbable metallic cardiovascular stents: Insights from recent human and in vivo studies, Alexander A. Oliver, Malgorzata Urszula Sikora-Jasinska, Ali Gökhan Demir, and Roger J. Guillory II

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In vitro behavior of bioactive hybrid implant composed of additively manufactured titanium alloy lattice infiltrated with Mg-based alloy, Tohar Perets, Noa Ben Ghedalia-Peled, Razi Vago, Jeremy Goldman, Amnon Shirizly, and Eli Aghion

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Oxidation Chemistry of Catechol Utilized in Designing Stimuli-Responsive Adhesives and Antipathogenic Biomaterials, Rattapol Pinnataip and Bruce Lee

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Catechol-Based Antimicrobial Polymers, Seyedehfatemeh Razaviamri, Kan Wang, Bo Liu, and Bruce P. Lee

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Toy Story: Improvements to a First-Year Engineering Design Project Based on Student Feedback, Ariana Gabrielle Smies, Erin Vandenbusch, and Michelle E. Jarvie-Eggart

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Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review, Kevin W. Sunderland, Jingfeng Jiang, and Feng Zhao

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Impact of calcific aortic valve disease on valve mechanics, Brennan Vogl, Nicholas R. Niemi, Leigh G. Griffiths, Mohamad A. Alkhouli, and Hoda Hatoum

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Augmenting 3D Ultrasound Strain Elastography by combining Bayesian inference with local Polynomial fitting in Region-growing-based Motion Tracking, Shuojie Wen, Bo Peng, Hao Jiang, Junkai Cao, and Jingfeng Jiang

Works from 2020

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In situ deactivation of catechol-containing adhesive using electrochemistry, Mohammad Saleh Akram Bhuiyan; James D. Roland; Bo Liu; Max Reaume; Zhongtian Zhang; Jonathan D, Kelley; and Bruce P. Lee

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Elevated L-lactate Promotes Major Cellular Pathologies Associated with Neurodegenerative Diseases, Andrew Chapp, Jessica Behnke, Kyle Michael Driscoll, Taija Marie Hahka, Zoe LaLonde, Zhiying Shan, and Qing Hui Chen

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Effect of Left and Right Coronary Flow Waveforms on Aortic Sinus Hemodynamics and Leaflet Shear Stress: Correlation with Calcification Locations, Dorma C. Flemister, Hoda Hatoum, Varshini Guhan, Banafsheh Zebhi, Joy Lincoln, Juan Crestanello, and Lakshmi P. Dasi

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Hydroxyl Radical Generation through the Fenton-like Reaction of Hematin- And Catechol-Functionalized Microgels, Pegah Kord Forooshani, Rattapol Pinnaratip, Elizabeth Polega, Ariana Tyo, Eric Pearson, Bo Liu, Tinu Ololade Folayan, Lei Pan, Rupak Rajachar, Caryn L. Heldt, and Bruce P. Lee